Biopharma Industry Solutions

Bionet's solutions for the biopharma industry

Biopharmaceutical companies play a crucial role in the bioprocessing industry, bringing to market monoclonal antibodies, vaccines, recombinant proteins, and cell and gene therapies, among other products. To achieve this, their daily bioprocessing challenges include pursuing high productivities and yields, ensuring scalability without compromising product quality or process efficiency, and meeting the highest quality standards, including purity, efficacy and safety in all batches. All this while leveraging advanced digital technologies that Pharma 4.0 dictate to improve all these aspects along the entire pharmaceutical manufacturing chain, from R&D to production.

Why Bionet?

By combining our expertise, collaboration with the biopharma industry and research organisations and experience working with the biopharma industry and innovative single-use technologies, Bionet proposes a complete solution for your bioprocesses.

End-to-end Solutions

Accelerate time to market

  • Reduce time on cleaning and sterilisation with single-use technologies
  • Decrease process time by saving transfer steps with Celltainer's expansion channel

Improve the quality and support

  • Maintain consistent process conditions, which leads to better control over product quality, following the Quality by Design (QbD) approach of pharma 4.0 with Bionet's proprietary bioprocess software
  • Ensure sterility and decrease contamination risk with Bionet's single-use technologies

Regulatory Compliance

  • Navigate regulatory requirements and establish excellence, quality and safety of the authorities and your demands with our qualification service support 
  • Ensure unparalleled quality and compliance with Bionet's products that are designed, constructed and qualified in strict accordance with GMP guidelines

Optimise the cost

  • Reduce cost while saving bags and seed train steps, enabling up to 100-fold volume expansion in one bag, and thereby both acquisition and operational costs.
  • Accelerate your process optimization and enhance reproducibility with Rosita 2.0’s innovative software.

Concrete solutions by our technologies

Expansion channel of Bionet's Celltainer

View CT-2 Cell expansion processes often involve high contamination risks and long operational times due to multiple transfer steps. Bionet’s Celltainer addresses these issues with its patented expansion channel system, enabling scalable working volumes from 0.15 to 15 litres within a single bag and up to 25 litres with customizable 3D designs. This innovation reduces process steps and contamination risks while facilitating seamless scaling from research to production, aligning with Pharma 4.0’s focus on flexible and integrated manufacturing solutions. The system features bottom-mounted sensors with a “cup” design for precise control, enhancing efficiency and cost-effectiveness throughout biopharma production.

TFF pump, for gentle cells handling

View M1 TFF System Bionet’s TFF systems allow you to choose a pump, suitable for your shear sensitivity requirements and tailored to meet the specific needs of different applications. This feature allows you to get control over the shear forces applied to cells, ensuring minimal stress and preserving cell integrity. Such adaptability is important for those biopharma processes, where maintaining cell viability and product quality is essential.

Range of single-use options

Bionet offers several single-use technologies tailored to the biopharma industry. Advanced single-use vessels for F0-baby and F1 bioreactors and Celltainer's innovative single-use bags allow for minimising contamination risk, which is crucial for the biopharma sector.

Designed, built and qualified under GMP guidelines

Our GMP approach is structured so that design, construction and control can be adapted to your specific project and regulatory needs to allow the validation of your processes from standard to GMP.

Advanced control and understanding of your process and global digitization guarantee.

ROSITA software licenses are developed to solve, with a very user-friendly yet advanced and flexible approach, shared challenges in terms of monitoring, visualization and control of bioprocesses among others. In Biopharma, Quality by Design guidelines require close monitoring and deep process knowledge as a mechanism to ensure product quality, while Pharma 4.0 pushes for increased overall digitization. This translates into the need for advanced monitoring through PAT measurements and their integration into sophisticated control strategies. The connectivity and integration solutions offered by ROSITA, to connect to a wide range of PATs but also to other SCADAs and PMS, together with the numerous tools available in terms of monitoring, automation, visualization and data management, make this software one of the best options on the market.

Bioreactors for Biopharma

F0

Benchtop Bioreactor | Enhanced expandability

F1

Laboratory Bioreactor | Universal Bioreactor for your lab

F2

Lab to Pilot Bioreactor | Steam-in-Place Bioreactor

F3

Pilot to Industrial Bioreactor | Steam-in-Place Bioreactor

FS

Industrial Bioreactors | Above 200 litres or to meet specific requirement

Celltainer is our single-use pilot bioreactor with patented two-dimensional rocking technology

Benchtop Bioreactor

Production Bioreactor | Working volume from 0.15L to 15L in one bag

Production Bioreactor | Working volume from 30L to 150L in one bag

TFF for Biopharma

MS

Industrial TFF | Flexible membrane selection

M1

Benchtop to Pilot TFF | Flexible membrane selection

New F1 Features

Discover the New F1 Bioreactor - Engineered for Excellence