Bioreactors
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Bionet's solutions for the biopharma industry
Biopharmaceutical companies play a crucial role in the bioprocessing industry, bringing to market monoclonal antibodies, vaccines, recombinant proteins, and cell and gene therapies, among other products. To achieve this, their daily bioprocessing challenges include pursuing high productivities and yields, ensuring scalability without compromising product quality or process efficiency, and meeting the highest quality standards, including purity, efficacy and safety in all batches. All this while leveraging advanced digital technologies that Pharma 4.0 dictate to improve all these aspects along the entire pharmaceutical manufacturing chain, from R&D to production.
By combining our expertise, collaboration with the biopharma industry and research organisations and experience working with the biopharma industry and innovative single-use technologies, Bionet proposes a complete solution for your bioprocesses.
View CT-2 Cell expansion processes often involve high contamination risks and long operational times due to multiple transfer steps. Bionet’s Celltainer addresses these issues with its patented expansion channel system, enabling scalable working volumes from 0.15 to 15 litres within a single bag and up to 25 litres with customizable 3D designs. This innovation reduces process steps and contamination risks while facilitating seamless scaling from research to production, aligning with Pharma 4.0’s focus on flexible and integrated manufacturing solutions. The system features bottom-mounted sensors with a “cup” design for precise control, enhancing efficiency and cost-effectiveness throughout biopharma production.
View M1 TFF System Bionet’s TFF systems allow you to choose a pump, suitable for your shear sensitivity requirements and tailored to meet the specific needs of different applications. This feature allows you to get control over the shear forces applied to cells, ensuring minimal stress and preserving cell integrity. Such adaptability is important for those biopharma processes, where maintaining cell viability and product quality is essential.
Bionet offers several single-use technologies tailored to the biopharma industry. Advanced single-use vessels for F0-baby and F1 bioreactors and Celltainer's innovative single-use bags allow for minimising contamination risk, which is crucial for the biopharma sector.
Our GMP approach is structured so that design, construction and control can be adapted to your specific project and regulatory needs to allow the validation of your processes from standard to GMP.
ROSITA software licenses are developed to solve, with a very user-friendly yet advanced and flexible approach, shared challenges in terms of monitoring, visualization and control of bioprocesses among others. In Biopharma, Quality by Design guidelines require close monitoring and deep process knowledge as a mechanism to ensure product quality, while Pharma 4.0 pushes for increased overall digitization. This translates into the need for advanced monitoring through PAT measurements and their integration into sophisticated control strategies. The connectivity and integration solutions offered by ROSITA, to connect to a wide range of PATs but also to other SCADAs and PMS, together with the numerous tools available in terms of monitoring, automation, visualization and data management, make this software one of the best options on the market.
Celltainer is our single-use pilot bioreactor with patented two-dimensional rocking technology
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