Bioreactor's Software Rosita

The software solution for the F0 BABY, F1 and M1 benchtop bioreactors, adaptable to their common or special microbial and cell culture configurations.

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While offering simplicity and flexibility at all levels, ROSITA increases experimental consistency via automation, improving reproducibility, and enhances deep understanding of the cell and the process parameters, facilitating process characterization and thereby its future optimization and scalability.

Key Features

Its design is:

  • Highly intuitive in all its configuration and monitoring options across the screens, thanks to a range of symbols, notifications, and alarms.
  • Scalable, by following the same workflow as in the industrial bioreactors and the same control, visualization, registration and management tools.
  • Expandable functionalities, derived from its modular design that allows the Plug&Play of additional sensors and bSmart modules.

Basic configuration

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A variety of automation possibilities for a process control

Let’s take the control of Dissolved Oxygen (DO) as an example. No matter whether you want to configure the gas flows directly, control the DO at a certain value by establishing control loops with associated actuators, or do this but at different levels throughtout the process on the basis of time or other events, you will find a range of tools to configure your control strategies.

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A number of visualization tools to allow for real-time monitorization of your process and a deep analysis

ROSITA developers understand the benefits that the visualization and analysis of a bioprocess can bring in R&D and scale-up studies. Thus, ROSITA provides capabilities to: Visualize all process parameters in real time, in summary tables and trend graphs with many features that facilitate the navigation across data. Perform comparative analysis by allowing the plotting of up to 3 different batches.

Calculate some process parameters. These include summary tables, trend graphs and comparative graphs, which allow the comparison between past and current batches.

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A modular design that allows large adaptability to many different types of processes and needs, by the automatic recognition of all bSMART Modules and PATs

ROSITA supports the modularity of the equipment by upgrading its interface and functionalities upon the connection of additional instrumentation and/or actuators. Each of these come with their own control strategies and enable the integration of its data into ROSITA’s visualization and data registration tools.

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Easy data exportation and registration tools that facilitate the management and analysis of bioprocess data

ROSITA registers all actuators’ and parameters’ data in ordered CSV format, which facilitates many data analysis tasks in R&D and scale-up activities.

Moreover, the exportation of recipe programmes from one bioreactor to another increases operation efficiency and experimental reproducibility.

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Remote access facilitates monitorisation 24/7 and process control outside the laboratory

ROSITA is designed to be accessible both on-site and remotely via IP address within the LAN.

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ROSITA Multibioreactor F0 and F1 TWIN enable control of multiple bioreactors

The ROSITA Multibioreactor upgrade enables the control of the 3x F0-BABY bioreactors from the same screen and Software license. In the F1 TWIN version of the F1 bioreactor series, the 2 bioreactors are controlled similarly, from the same BCU and software.

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Personal profiles to facilitate operation of processes in a team

Users can be created, protected with a password and assigned a user level with the corresponding operational permits. This is specifically useful, when various processes are controlled simultaneously with F0 Multibioreactor or F1-TWIN.

Add-ons

A full ecosystem of tools within a single design environment.

bScale

Module for the connection of scales

bCPM

Increase your bioprocess productivity

bVSP

Expand your asignable pumps

bBreath

Carry out O2/CO2 composition analysis

Clean in Place

Fully integrated CIP system all in the same frame.

New F1 Features

Discover the New F1 Bioreactor - Engineered for Excellence