F0

Benchtop Bioreactor | Enhanced expandability

Multi useAutoclavableSingle-use

Stirred

Benchtop

Modular and ergonomic system of premium quality

What is it used for?

The F0-baby series comprises optimal entry-level autoclavable fermenters/bioreactors for microbial and cell-culturing bioprocessing activities. The system provides a cost-effective and user-friendly alternative to the bigger and more complex equipment, being an ideal solution for R&D as well as for training and education purposes. This bioreactor offers both multiuse and single-use options, providing flexibility and convenience for the agro-, food-, cosmetics-, and biopharma industries.

Customisation and flexibility

Tailor your bioprocessing needs with ease using the F0-Baby bioreactor. Designed for advanced fermentation and cell culturing, it offers simplicity, a small footprint, and a sleek design. The F0-Baby's modular Plug&Play concept allows for future expansion of functionalities, and it accommodates various vessel volumes, geometries, and accessories for great flexibility. Last but not least, our multi-bioreactor configuration enables control of up to three units under one PC, allowing to sharing of process recipes, online data comparison, and more. All these features make the F0-baby a versatile choice for a wide range of bioprocessing activities.

Key benefits

This compact bioreactor is designed for ergonomic operation and maintenance while integrating advanced design details and reliable technologies. Its space-saving design is specifically beneficial for laboratories with limited space, optimising equipment layout and providing greater flexibility in laboratory set-up.

F0-baby combines cost-effectiveness with premium quality. It features advanced technology and robust software capabilities while surpassing other basic models in the market in value.

Discover ease in bioprocessing with our intuitive solution. Seamlessly integrated with user-friendly software design and easy maintenance, all within a compact footprint.

Our modular Plug&Play design paves the way for seamless expandability, ensuring you’re prepared for future enhancements and functionalities. It offers exceptional versatility for various applications, eliminating the need for purchasing multiple specialised equipment.

Product features

Complete Software for improved control

This bioprocess automation software Rosita integrates full SCADA capabilities for control, visualisation, and data logging during bioprocessing. It features an intuitive interface that enhances lab efficiency, providing complete control over bioprocessing parameters, including recipe management, user profiles, and remote control.

Interchangeable borosilicate vessels in a range of volumes for different uses

The vessels are available in a wide range of working volumes and different geometries for microbial and cell cultures. Its interchangeability derives from the existence of shared vessel supports and agitator motors. F0 allows you to effortlessly manage up to three bioreactors from a single computer with our multi-bioreactor control feature.

A functional lid for ergonomic and flexible operation

The design of the lid offers a wide variety of operation possibilities, as well as ergonomic handling and maintenance. A high number of ports provides functional versatility, as the ports allow for the input and output of information and material, including sampling.

A precise and adaptable agitation module with simple maintenance

Top agitation provides additional flexibility to agitator geometry. For control see ROSITA.

A premium quality flexible pump configuration with advanced control

The F0-BABY is delivered with 3 precise and linear peristaltic fixed speed pumps and the option of the integration of up to 4 additional pumps with variable speed, which allows Fed-batch and Continuous Processes among others.

A simple, effective and easy-to-maintain temperature control system

The temperature control, with a range of °C: 10 – 55 °C, is exerted efficiently for most types of cells. It consists of an internal pneumatic circuit, a cooling finger and a heating blanket as actuators.

Possibilities for future expansion – Plug&Play

The presence of accessible spare signals and wired connectors allows for future integration of additional instrumentation and actuators, and Bionet’s bSmart Modules in a Plug&Play fashion.

Models

Cell culture stirred bioreactor from 2 to 8 liters

For enhanced protein production from mammalian cell lines like CHO or HEK293, ensuring optimal results via the right geometry and vessel accessories, such as microspargers and pitch-blade or marine impellers to improve mass transfer and avoid damaging the cells.

Models

Microbial stirred bioreactor from 1 to 10 liters

Suitable for a large variety of microorganisms in the pharma, industrial, food or agricultural spaces. Leveraging common bioreactor technology, it accommodates the different processes and strains thanks to dedicated accesories and vessel geometry.

Models

Single-use 2 liters bioreactor

Single-use vessel provides functionality comparable to glass bioreactors with all the benefits of disposable solutions, addressing the needs of pharmaceutical and biotech industries.

Add-ons

Find all the additional modules that your bioreactor needs.

bScale

Module for the connection of scales

bCPM

Increase your bioprocess productivity

bVSP

Expand your asignable pumps

bBreath

Carry out O2/CO2 composition analysis

FAQs

A big advantage of F0 is the ability to construct it following your needs. Get an entry-level bioreactor that has better configuration and software capabilities than most of the low-cost models in the market. You can add more functionalities later by just purchasing and connecting the new module/probe to the control unit. Due to the Plug&Play concept, bSmart modules, additional instrumentation, available spare signals and lid ports, our bioreactor remains a flexible and universal solution for different purposes.

Monitoring critical parameters like CER (Carbon Dioxide Evolution Rate) can offer sensitive insights into your culture’s metabolic activity, aiding in optimising feeding strategies. For non-homogeneous cultures, combining CER data with optical density measurements enhances accuracy. Additionally, tracking microbial respiration parameters such as CER, OUR (Oxygen Uptake Rate), and RQ (Respiratory Quotient) provides a comprehensive view of your microorganism’s development, overcoming limitations posed by heterogeneous cultures.