CT-3

Celltainer's patented 'cup design' for the single-use bottom-mounted sensors allows for starting with reduced working volumes at stable readings and control. The sensors are covered with medium during movement for stable read-out of pH and DO values and the medium in the cup design is refreshed with every movement.

With the use of bottom-placed probes, minimal starting volumes of 0.25L and a maximum of 25L in the same bag are feasible. Save SIP, and CIP validation steps by using the CT2 as a seed train.

Celltainer's patented 2D movement profile ensures kLa values of >400 h⁻¹ supporting high cell-density microbial cultivations in single-use equipment.

Celltainer patented 2D rocking movement, which no one else can provide, offers unparalleled power input per volume and G/L mass transfer above 400 h⁻¹ kLa so that higher density and protein production levels are achieved at low shear in single-use technologies.

By offering adjustment of rocking angle, speed, highly customisable bags and a range of plug&play add-ons, the Celltainer is highly configurable and expandable which makes it possible to handle microbial, mammalian, plant and insect cells in the same device, adapting to your evolving project and/or multipurpose plant.

Our E.coli cultivation studies demonstrate consistent optical densities across different scales: 2L STR, 12L CELL-tainer CT2, and 120L CELL-tainer CT3 models. Leveraging advanced CFD models for CT1 and CT2, we ensure scalable results in mixing time, power input, and mass transfer under various conditions. These models are validated through rigorous experiments, ensuring reliable scale-up for our customers. The CT3 stands as the largest model in the CT series. DOI: 10.1002/cite.201200149

2D movement creates waves that break the foam, typically eliminating the need for antifoam agents. Since foam is not generated by aeration rate due to headspace aeration rather than sparging, no additional antifoam is required.

The CT2 bioreactor offers a stackable design (up to 3 units) to maximize lab floor space. It features a plug-and-play setup, eliminating the need for sterilization, as bags are gamma-sterilized and come with single-use sensors (pH, DO). With no moving parts in the bag, you benefit from reduced consumable costs and minimized risk of failures.

CT2 features CFD models that ensure mixing time, power input, and mass transfer scalability across various rocking angles, speeds, working volumes, and bag shapes. We validate these models through running experiments to support seamless scale-up for our customers. The CT3, as the largest model in the CT series, extends this scalability to larger production needs.

Reduce your financial risks by renting one of our CT2 bioreactor before deciding to purchase a CT3. Convince yourself with proof-of-concept studies or transfer your in-house process to the Celltainer CT2. We guarantee scalability through our product range.

Our approach to GMP is structured so that design, construction and control can be tailored to your specific project and regulatory needs to enable validation of your processes from standard to GMP.