Bioprocess Automation

Lab & Pilot Software

ROSITA

For the automation, control, visualization and analysis of your bioprocess

A powerful, intuitive and flexible software for scientists to control and truly understand their bioprocess and the potential of it

Automation, control, visualization and analysis of your bioprocess

ROSITA is the automation SW that comes with the F0-BABY and F1 lab and pilot equipment series, complementing them with the following advantages.

  • Increasing consistency in your experiments, which in turn enhances reproducibility of your results and thereby approval of your bioprocess.
  • Ensuring understanding of your strain’s nature and your bioprocess’ parameters evolution and relationship in real time, facilitating optimization tasks and design of next experiments.
  • Enabling predictability of your bioprocesses’ evolution, results and product characteristics.
Bioprocess parameters control loops, recipe-based bioprocess automation and cascade mode control of dissolved oxygen

YOU’VE GOT IT UNDER CONTROL!

ROSITA enables an efficient automation and tight control over the process via:

  • A variety of control loops possibilities beyond the basic parameters of pH, temperature, agitation, gas flows and dissolved oxygen.
  • The possibility to create and manage recipes, in which control loops are configured across several stages and transitions between these stages in the basis of events and/or time are established.

TAKE ADVANTAGE!

ROSITA embraces the plug and play concept by upgrading its interface and functionalities upon the connection of additional instrumentation and/or actuators. ROSITA allows:

  • The visualization and use of process data from additional in-situ Process Analytical Technologies (PATs), such as total/viable biomass counters, conductivity sensors, CO2 probes, etc.
  • The use of additional proprietary modules that allow further process functionalities and modes (e.g. advanced gas strategies, continuous process mode, etc).
  • The introduction of offline data, for its visualization and usage in advanced control strategies
Process Analytical Technologies control loops, optical density sensors, CO2 sensors, conductivity sensors, Continuous Process Module, bioprocess offline data
Bioprocess visualization in trend graphs and comparative graphs

GET KNOWLEDGEABLE:

ROSITA developers realize about the benefits that the visualization and analysis of a bioprocess can bring in R&D and scale-up studies, and have therefore provided ROSITA with capabilities to:

  • Visualize all process parameters in real time, in trend graphs with many features that facilitate the navigation across data.
  • Perform comparative analysis via a graph that allows the plotting of up to 3 different batches.
  • Calculate process parameters.

BE CONNECTED!

ROSITA is designed to:

  • Be accessible both on-site and remotely.
  • Control simultaneous bioprocessing in its multibioreactor configuration (up to 4 bioreactors).
Control parallel bioprocessing from more than one bioreactor;fermenter;fermentor
Data registration in CSV format and extraction to Excel

MANAGE YOUR DATA!

ROSITA deals with bioprocess data in efficient and intuitive ways:

  • Perform data registration in ordered CSV format.
  • Upon demand, it delivers data in more advanced formats such as reports.

TECHNICAL SPECIFICATIONS

MODEL ROSITA Bronze Package

MODEL ROSITA Silver Package

MODEL ROSITA Gold Package

navigating screens
navigating screens
Available screens
  • Main (process synoptic)
  • Recipe
  • Graphs (trend and comparative)
  • Alarms
  • Users management
  • Settings
Available screens
  • Main (process synoptic)
  • Recipe
  • Graphs (trend and comparative)
  • Alarms
  • Users management
  • Settings
Available screens
  • Main (process synoptic)
  • Recipe
  • Graphs (trend and comparative)
  • Alarms
  • Users management
  • Settings
automation
automation
Cascade control of DO levels
  • -
Cascade control of DO levels
  • Agitation
  • Gas Flows
  • Nutrient flow
Cascade control of DO levels
  • Agitation
  • Gas Flows
  • Nutrient flow
Control loops associated to optional sensors and external modules
  • -
Control loops associated to optional sensors and external modules
  • Optional
Control loops associated to optional sensors and external modules
  • Optional
Direct/Manual set point configuration of actuators
  • Agitator
  • Pumps
  • Gas flows
Direct/Manual set point configuration of actuators
  • Agitator
  • Pumps
  • Gas flows
Direct/Manual set point configuration of actuators
  • Agitator
  • Pumps
  • Gas flows
Recipe management
  • -
Recipe management
  • Included by default
Recipe management
  • Included by default
SP profiling of process parameters and activation of associated actuators (pumps, valves, etc)
  • pH
  • Temperature
  • Dissolved Oxygen
  • Level
SP profiling of process parameters and activation of associated actuators (pumps, valves, etc)
  • pH
  • Temperature
  • Dissolved Oxygen
  • Level
SP profiling of process parameters and activation of associated actuators (pumps, valves, etc)
  • pH
  • Temperature
  • Dissolved Oxygen
  • Level
visualitation and analytical tools
visualitation and analytical tools
Comparative Graph
  • -
Comparative Graph
  • Included by default
Comparative Graph
  • Included by default
Data table (with min and max values)
  • Included by default
Data table (with min and max values)
  • Included by default
Data table (with min and max values)
  • Included by default
Off-line data representation
  • -
Off-line data representation
  • Optional
Off-line data representation
  • Optional
Trend graph
  • Included by default
Trend graph
  • Included by default
Trend graph
  • Included by default
data management
data management
Export of graphs as pictures
  • -
Export of graphs as pictures
  • -
Export of graphs as pictures
  • Optional
Export of raw data in ASCII and Excel formats
  • Included by default
Export of raw data in ASCII and Excel formats
  • Included by default
Export of raw data in ASCII and Excel formats
  • Included by default
Generation of reports
  • -
Generation of reports
  • Optional
Generation of reports
  • Optional
alarms
alarms
Availability
  • Included by default
Availability
  • Included by default
Availability
  • Included by default
access and user management
access and user management
Personal operation profile and password protection
  • -
Personal operation profile and password protection
  • Included by default
Personal operation profile and password protection
  • Included by default
User/level access rights
  • -
User/level access rights
  • -
User/level access rights
  • Optional
cfr21.11
cfr21.11
Available
  • -
Available
  • -
Available
  • -

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