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Turbidostat Strategy in Continuous Bioprocessing

Turbidostat setting via Bioreactor Weight Mode

AGENDA

1. Introduction
2. Types of Continuous Bioprocessing strategies

  • Chemostat
  • Turbidostat
  • Auxostat
  • Perfusion

3. Principles of Turbidostat
4. The scientific concepts in Turbidostat (e.g. estimation of Specific Growth Rate, the relationship between Optical Density and Biomass Concentration, etc).
5. The different Technologies to control the bioreactor volume

  • Overflow mode
  • Level probe mode
  • Slave Pumps mode (i.e. equivalent addition and withdrawal)
  • Bioreactor Weight mode

6. The Advantages and Disadvantages of the above-mentioned modes
7. Conclusions

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