Bionet F3 models is a unique concept for those seeking for premium quality a Steam In Place (SIP) Bioreactor of industrial scale and conception, with the quality of a standardized product but with the flexibility to develop and scale-up new bioprocesses.
A system with a state-of-the-art technology core technology and many details, has been created to be the market reference in pilot or small industrial fermentation and cell culture. It comes in 3 models with 50, 100 and 200 l maximum working volume.
If what you need is a fully customized bioreactor, beyond the standard features, or bigger volumes than 200 l . See more…
The F3 are meant to be the cornerstone of your industrial production and advanced pilot activities. For that it integrates proven industrial technology solutions
Bottom agitation system, with a servo gives a complete (from almost zero to hundreds of rpms) broad speed range and power input, adapted to the needs of your culture. Being bottom placed allows for clean and light top lid, giving you easier maintenance and numerous ports. Available with standard impellers (Rushton, marine, pitch blade) or special designs on demand. Mechanical seal can be single, double (SIP) or magnetic coupling.
The F3 has the needed add-ons for giving you the technology for the most demanding gas control. With our Advanced Gas Module for Cell Culture (with Air, N2, O2 and CO2, and inlets in sparger and doom) you will be able to the control the parameters you need for optimizing and qualify your protein production.
The temperature control system includes a jacket which covers practically the whole vessel, combined with a primary circuit with heater, heat exchanger for cooling water and recirculation pump. All this provides accurate temperature control and big heat exchange capabilities; even for the most demanding cultures.
As its smaller sister the F2 the F3 can integrate a CIP system. All in the same frame, with no extra-footprint, using the dossing pumps for acid and base and the pH probe, the CIP can be made without external intervention. All controlled from our control SW MARTA in which the CIP Module allows for programming of recipes. which can be created and saved to allow for standardization of cleaning and productivity.
Providing the possibility to integrate a complete range of instrumentation and actuators, and allowing all kinds of associated control strategies helps you to better understand, improve and control your processes.
Example of instruments which can be added beyond the standard configuration are: Pressure, Optical Density, Viable Cells, Dissolved CO2, Exhaust gas composition, Redox, Weight for reactor and additions and many others.
Most of these instruments have a corresponding MARTA SW module. These specific SW modules allows the user to select parameter as part of your control strategies and gives additional calculated information (e.g. OTR or OUR) in real time.
MARTA is the Automation SW which comes installed in the F3 units. In this model has off-the-shelve solutions for Cell Culture, Fermentation which can be expanded with additional modules for local CIP, new instrumentation or advanced gassing or dosing control.
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