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Bioreactors
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Laboratory Bioreactor | Universal Bioreactor to your lab
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Redefine Versatility with F1
Tailor your bioprocessing needs with ease. Our high configurability accommodates various vessel volumes, bioreactor types, and combinations, offering unparalleled flexibility.
Expand Easily with bSmart Modules
Start with a basic configuration and add functionalities as needed using Plug & Play modules, without sending the unit back to the factory.
Empower Your Process Control
Harness the potential of advanced software and instrumentation, providing you with a user-friendly interface to expand your knowledge and achieve precise process control.
Save Space in Your Lab with F1’s Smart Design
The F1 bioreactor features an ergonomic and compact design, optimised to fit seamlessly into any lab setup. Choose between the Single version or a Twin design, that allows two vessels in one BCU. Seamlessly run parallel experiments by sharing process recipes, real-time graphic comparison, and more.
Optimise Connection Efficiency
Simplify operations with accessible and standardised connectors, ensuring quick setup, reliable integration, and minimal downtime during installation or maintenance.
New F1 Features
With flexible configuration and multiple expansions in instrumentation and actuators, and native for process intensification, it will adapt to your evolving needs. It comes with a user-friendly interface to program automation from simple to highly complex processes, and AI connectivity.
The F1 is available in single and twin configurations and is equipped with Rosita 2.0 software, enabling parallel operation of up to 24 bioreactors. As part of a complete bioreactor portfolio with working volumes ranging from 0.25 L to 10,000 L, it provides a seamless scale-up path from R&D to industrial production.
Redefine Versatility with F1
Tailor your bioprocessing needs with ease. Designed for ultimate flexibility, F1 supports:
Whether you’re working with cutting-edge cell culture systems or high-yield microbial processes, F1 adapts to meet your needs seamlessly.
F1 enables automation of processes ranging from very simple to highly complex through unlimited recipes, equation-based control, and soft sensors and is conceived for seamless connectivity for AI based management, control and DOE. This decreases complexity for the operator and reduces manual intervention, accelerating process development and optimization, in up to 24 parallel units.
The F1 is “Future Ready” for the new needs and additional complexity the evolution in your processes may bring. Is Native for Process Intensification, supports multiple bioreactor technologies (jacketed and single wall STR, airlift and STR and 2D rocking SUBs) and a very large options for expanding your initial set-up. Up to seven freely assignable pumps per bioreactor, 5 MFCs, 5 digital and 2 analog sensors, 3 scales with a plug-and-play ecosystem make the F1 the “non-regret” bench-top bioreactor control unit.
F1 is designed to be qualified under GMP regulatory guidelines, with construction standards, 21 CFR Part 11 software and internal commissioning leverageable for qualification (DQ/IQ/OQ). The complete P.A.T. capabilities and process intensification options, provide the bases to reduce risk and accelerate your Biopharma process scale-up, helping users meet regulatory expectations while simplifying audits and lifecycle management.
A well compartmentalized hardware design ensures reliable operation and easy access to all control unit components. This simplifies maintenance, enables remote diagnostics, and helps minimize downtime through efficient technical support.
Advanced software
Discover Rosita 2.0, the software used in the F1 bioreactor. It´s powerful, flexible and intuitive
The lid design offers the perfect balance between flexible operation and easy handling, operation and maintenance. The number of ports provides functional versatility, as the ports allow for the exchange of information as well as material, such as sampling.
A precise motor serves the complete vessel volume range with turbine options including Pitched-blade impeller, Rushton, Marine and other customised options and a whole range of rpms. In addition, top agitation provides flexibility to the agitator geometry.
The F1 is delivered with 2 precise peristaltic fixed speed pumps, enabling reliable repetition and scaling. The integration of 2 extra variable speed pumps in the control unit and 3 additional external allow for Batch, Fed-Batch or Continuous Processes.
The Fl is equipped with a gas module with more than 5.000 combinations thanks to the flexibility given by the number of mass flow controllers, bioreactor inlet, and gas flows for each lines, covering all your needs.
Temperature control consists of an internal jacket with a closed water circuit, covering a temperature range of up to °C: 10 – 80 °C, efficient with all types of cells. For more technical information and experimental data ask Bionet.
The presence of accessible spare signals and wired connectors allows for future integration of additional instrumentation and actuators, and Bionet’s bSMART Modules in a Plug&Play fashion.
A sophisticated and comprehensive software solution that can rival the most advanced licensed products in the market while offering a more cost-effective alternative. Configurable control loops between several sensors and actuators of choice, beyond the standard. Programmable control loops via equations. Configuration of soft sensors that can be visualized but also used for control.
The F1 can be designed, constructed, and qualified in strict accordance with GMP guidelines, ensuring unparalleled quality and compliance.
The vessels are available in different types for stirred bioreactor, photobioreactor and airlift, as well as a wide range of working volumes and in interchangeable geometries for microbial and cell culture, thanks to shared vessel supports and agitator motors.
With the F1 you can control our patented 2D rocking movement bioreactor CT1, which makes it suitable for both high-density microbial and cell cultures. Moreover, explores the added capability to integrate a stirred vessel, further enhancing F1's suitability for cell culture applications.
Models
Microbial fermentation refers to the process by which different substrates are converted by a variety of microorganisms under anaerobic or aerobic conditions to desired products, for the the pharma, industrial, food or agricultural spaces. Leveraging common bioreactor technology, it accommodates various physiological and metabolic needs, with additional modules and PATs expanding its adaptability for specific strains and applications.
Models
Stirred cell culture bioreactors are essential for precise protein production from mammalian cell lines like CHO or HEK293, ensuring optimal results across pharmaceuticals, biotech, and research with versatile configurations and additional modules for specific needs.
Models
For shear-sensitive cells, airlift bioreactors offer a suitable solution, with common needs addressed by our bioreactor technologies. Additional functional modules and PATs cater to specific strain and application requirements.
Models
Single-use vessel provides functionality comparable to glass bioreactors with all the benefits of disposable solutions, addressing the needs of pharmaceutical and biotech industries.
Models
Our Single-use 2D rocking bioreactor is ideal for R&D, process optimization, and small-scale bioproduction.
Find all the additional modules that your bioreactor needs.
Differences between two of our bioreactors: the FO-Baby and the F1
One Control System — Multiple Vessels: F1’s Vessels Interchangeability
Versatile Pump Solutions with F1
Expandable Gas Module of F1
F1’s Plug&Play bSmart Modules for Changing R&D Needs
F0 and F1 testimonial by Fuensanta
One effective approach is to ensure a wide range of possibilities for all configuration categories, such as offering a fully configurable gas strategy, various flowrates for additions, and additional instrumentation options. This flexibility enables tailored solutions to meet the exact specifications of your project or task.
By maximizing the interchangeability of vessels and working with a diverse range of applications, including various models in Single or TWIN configuration, multiuse, or single-use technologies, and different application versions. This approach streamlines project workflow by providing flexibility in combining applications as needed.
By embracing expandability, a core concept integrated into all Bionet’s product lines. These solutions are designed around the Plug&Play concept, offering a range of bSMART modules to enhance functionalities at both hardware and software levels as different needs arise. This ensures adaptability and future-proofing for evolving process requirements.
Leveraging the strategic advantage of an expandable design can be a solution. By adopting an expandable approach, you can address dynamic requirements without requiring a substantial upfront investment. This flexibility allows for gradual scaling and investment alignment with project progress, helping to navigate budget constraints more effectively.
Overcoming the lack of experience working with bioreactors is possible with easily operated designs and compact footprints. Our Rosita software features a user-friendly interface that simplifies understanding and maintenance of bioreactor. This combination of features and tools facilitates a smoother learning curve, enabling users to become proficient in bioreactor operations quickly.
Your success is our priority, and our dedicated support team is here to assist you every step of the way. We’re committed to providing the assistance you require, ensuring that you have the resources necessary to overcome any challenges. To further support your journey, we offer a specialised fermentation course designed to clarify and answer all your technical questions, providing you with the expertise to achieve the best possible results.
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