Estas son las tecnologías.
The Celltainer CT-15 is our single-use pilot bioreactor with patented two-dimensional rocking technology. Ideal for R&D, process optimization, seeding and small-scale bioproduction. It can grow at very high density E. coli, P. pastoris, fungi, plant, mammalian or human stem cells. The CT-15 offers unprecedented mixing and mass transfer at low shear and without foaming.
Single-use systems are becoming another key technology in the field of mammalian cell culture and pharmaceutical applications, being especially suitable for biopharmaceutical products, where driving industry trends demand flexible, speedy and simple deployment.
The application of single-use bioreactors reduces the risk of cross contamination and enhances process safety in highly potent biopharmaceutical ingredients with extensive qualification and validation procedures. Advantages include reduced preparation and maintenance times.
For cells that are too sensitive to the shear stress and heat generation caused by the mechanical agitation, airlift bioreactors may be the most suitable solution.
Except for the agitation module, many common needs by these strains are already solved by our common bioreactor technologies. Moreover, special needs for each strain and application can be solved by the vast number of additional functional modules and PATs that Bionet’s bioreactors are able to integrate.
Cell Culture processes usually refer to the processes by which mammalian cell lines, such as CHO or HEK293, are used for the production of complex proteins given that they possess the machinery for translational modifications.
The sensitity of mammalian cells to physicochemical conditions in the extracellular environment (e.g. osmotic and toxic ones) results in the need for some considerations in the bioreactor design that differs from microbial ones.
Standard needs are considered in the standard configuration fo the equipment, whereas special needs for each cell type and application can be solved by the vast number of additional functional modules and PATs that Bionet’s bioreactors are able to integrate.
Microbial fermentation refers to the process by which different substrates are converted by a variety of microorganisms under anaerobic or aerobic conditions to desired products, for the the pharma, industrial, food or agricultural spaces.
These processes are carried out by a vast group of microorganisms, including bacteria, yeast and microalgae among others. Although these are very diverse in their physiology and metabolism, they all share some needs that can be solved by a common bioreactor technology. Moreover, special needs for each strain and application can be solved by the vast number of additional functional modules and PATs that Bionet’s bioreactors are able to integrate.
The different process conditions required by the different strains and product production pathways require of different bioreactor types and configurations.
FS are Bionet special models are Bioreactors engineered and built to measure, when working volumes are bigger than 200 l or for specific needs which demand a special design at any scale.
The software solution for the F0 BABY, F1 and M1 benchtop bioreactors, adaptable to their common or special microbial and cell culture configurations.
The perfect solution for first Steam In Place (SIP) stainless steel bioreactor/ fermenter for the scaling up of bioprocesses and for small production applications for a range of microbial and cell culture applications across different biotech sectors.