Deciding the configuration of your bioreactor can be a challenging process, especially when looking fora benchtop system to take the first steps at this scale. For that reason, configurability and expandabilityare the main factors to consider in this situation, so the optimization of your process does not getcompromised due to a rigid and closed system. […]
For the controlled production of microorganisms or living systems, gasification needs are always a criticalpart of the process regardless of its phase and its configuration can be challenging.Versatility and reliability are essential, on the one hand to find the conditions that optimize the processand on the other hand to reproduce the conditions entered from the […]
The yeast Pichia pastoris, has been successfully used as an efficientsystem to produce heterologous proteins [1]. Herein, we report thedevelopment of a semi-continuous process to improve the productionof recombinant proteins in P. pastoris in BIONET’s F1 bench-top3-liter bioreactor, equipped with a continuous process module (CPM).Six repetitive batches were conducted in a semi-continuous processby replacing 2/3 […]