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Continuous Process

 In Expert References
2088

The Continuous Process in the context of a bioreactor operation mode is used to prolong the production phase of a culture during its growth in a steady-state (at a constant rate and in constant conditions) to achieve higher biomass and/or metabolites amounts. There are two main process control strategies that can be implemented in Continuous Processing: the chemostat and the turbidostat methods.

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  • Expert References

    A Guide on Membrane Selection

    The most common membrane modules used in the Biotech industry for Tangential Flow Filtration (TFF) are cassettes, hollow fiber and ceramic membranes. Each membrane type has certain characteristics (see Table 1) in terms of batch volume, sensibility to and with product type, and its own lifetime, that makes it more or less suitable for a specific broth or application.

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  • Expert References

    5 steps into Scale-Up of Microbial Fermentation

    The Continuous Process in the context of a bioreactor operation mode is used to prolong the production phase of a culture during its growth in a steady-state (at a constant rate and in constant conditions) to achieve higher biomass and/or metabolites amounts. There are two main process control strategies that can be implemented in Continuous Processing: the chemostat and the turbidostat methods.

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  • Expert References

    Continuous Process

    The Continuous Process in the context of a bioreactor operation mode is used to prolong the production phase of a culture during its growth in a steady-state (at a constant rate and in constant conditions) to achieve higher biomass and/or metabolites amounts. There are two main process control strategies that can be implemented in Continuous Processing: the chemostat and the turbidostat methods.

    See more >

  • Expert References

    Chemical cleaning of membranes

    The chemical cleaning of the ceramic and/or hollow fiber membranes after a filtration stage must receive the attention it deserves. Having defined an effective cleaning protocol is just as important as having optimized filtration conditions when dealing with a tangential flow filtration process in your downstream. Moreover, I would dare to say, the latter is even more important. If after filtering we do not clean properly, the permeability of the membranes will go down batch after batch, resulting in changes to the membranes prematurely and thereby increasing the cost. The “permeability” […]

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Ceramic Membranes with different channel number and pore sizemethodology for scale up of microbial fermentation processes

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